抗DXd抗体

产品名称	Rabbit Anti DXd Antibody, mAb
产品货号	DTA0299
产品规格
价格

产品详情

名称	Rabbit Anti DXd Antibody, mAb
类型	Monoclonal
免疫宿主	Rabbit
免疫原	DXd conjugated to keyhole limpet haemocyanin(KLH)
亚型	IgG
纯化方法	Purified by Protein A
特异性	This antibody recognizes DXd and DXd structurally similar molecules. The antibody can bind to DS-8201.
验证应用平台	ELISA
缓冲液	1×PBS, pH7.4, containing 0.1% BSA, 50% glycerol and 0.03% Proclin 300.
储存方式	Shipped in ice bag. The antibody can be stored for 1-2 weeks at 2-8°C. For long term storage, store it at -20°C. Avoid repeated freezing and thawing cycles.

产品应用

应用	ELISA
推荐用量	0.1-2 ?g/ml

生物活性-ELISA

Rabbit Anti DXd Antibody, mAb

	DTA0299
EC50	3.39 ng/ml

Rabbit Anti DXd Antibody binds with BSA-DXd conjugate.
Coating antigen: BSA-DXd conjugate, 0.1 ?g/ml，100 ?l/well.
Rabbit Anti DXd Antibody dilution starts from 1000 ng/ml.

Rabbit Anti DXd Antibody, mAb

The competitive ELISA assay is developed by using free DXd block the binding of Rabbit Anti DXd Antibody to BSA-DXd conjugate.
Coating antigen: BSA-DXd conjugate, 0.1 ?g/ml, 100 ?l/well.
Detection Antibody: Rabbit Anti DXd Antibody, 100ng/ml 50ul/well.
Free DXd dilution start from 10000 ng/ml.

产品说明书产品说明书

DXd is a cell microtubule dynamics inhibitor and a soft sponge like anti-tumor drug. ADC loaded with DXd has a strong bystander effect and good clinical efficacy. Due to the release of payload after ADC administration, there is an increase in unbound payload and changes in ADC composition (i.e. DAR distribution). In order to address the challenges and difficulties in ADC drug PK analysis, a high-quality and high affinity anti DXd payload antibody can be used for ADC PK detection and DAR value analysis, which helps evaluate ADC efficacy, assess payload exposure at target sites, and is crucial for providing overall evaluation such as ADC stability.

物流平台：默认为京东物流。若有其他需求，请联系对接销售。
发货时间：确认订单并完成付款后1~2个工作日内安排发货。
发货方式：冰袋或干冰。